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When giving family planning advice, clinicians (including pharmacists) should consider the half-life of the drug in use, advice on length of contraception after the most recent dose, as well as existing evidence for use in pregnancy and breastfeeding and paternal exposure if the drug is to be continued, see Table 3[1,115,116]

Although rigorous statistical methods, including multivariable regression and stratified analyses, were employed to enhance the reliability and robustness of the results, the study design does not allow us to determine whether altered vitamin B12 levels directly influence testosterone concentrations or whether hormonal changes affect vitamin B12 metabolism

Veterinary Nutritional Formula

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