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AE also acknowledges funding from the European Union for HORIZON 2022 fLIMAGING3D (101073507) and HILIGHT (101135034, backed by Innovate UK as project number 10107542)

2019 May 15;12:1497-1508

Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing

Ibuprofen, in particular, possesses Nf-kB inhibitory activity that may further help reducing excess inflammation/cytokine release in COVID-19 patients ( there is no evidence supporting the association between Ibuprofen and increased risk of severity of COVID-19 , a position strengthened by a systematic review appeared 2 months later ( Several studies are accumulating and reappraising the importance of NSAIDs in COVID-19 management ( in silico screenings independently identified the COX-II inhibitor celecoxib as a potential anti-SARS-CoV-2 drug, and a very recent study still under peer review reports its beneficial effects plus famotidine in hospitalized patients ( Despite this accumulating evidence, paracetamol (PAC) was suggested as a safer and recommendable alternative for the early and domiciliary management of pain and fever in COVID-19 patients