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The close relationship between LH and poor metabolic control could suggest that all patients with clear-cut difficulties in achieving optimal control should be checked systematically for LH presence at all insulin injection sites

Antiinflammatory activity: Reduces proinflammatory cytokines and modulates immune responses in models of inflammatory bowel disease and systemic inflammation [3]

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These data clearly indicate an increase in circulating levels of specific chemokines and cytokines that are known to modulate systemic levels through immune cells, results in affecting local intestinal inflammation and tissue damage in IBD patients (304)