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In the process of physiological ageing, both systemic and tissue-specific systems show functional downfalls, which, when projected to the brain, translate into weakening defence and metabolic strain resulting from age-dependent declines of the cardio-vascular system and overall decreases in metabolism

FgGST1 and FgGST1-CB complexes showed an average RMSD value of 0.34 and 0.50 nm, respectively (Fig

The predominant use of Primary Health Care services, compared to lower demand for other levels of care, reinforces its strategic role in the management of this population

Cells were washed with PBS, detached with trypsin and centrifuged (5 min, 400 g), resuspended and covered with 5 M working solution of MitoSOX reagent in HBSS and incubated at 37 C for 10 min in FACS tubes