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Expected milestones during therapy: Baseline assessment and initial labs Early symptom change (26 weeks) Objective lab improvement (612 weeks) Dose optimization and protocol refinement (3 months) Long-term maintenance or tapering plans (612 months) Expectations While most patients experience progressive symptom relief, some begin to notice changes within 2 to 6 weeks, with measurable reduction in inflammation present by 8 to 12 weeks

In clinical trials, it is necessary and sufficient to rely on primary endpoints to determine whether a treatment or medication is effective

Furthermore, changes in AMPA and kainate receptors have been reported in ASD

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