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Hence, there is a need for fine-tuned engineering strategies that not only improve pharmacokinetic properties, but also enhance specific effector functions with a minimum of amino acid substitutions to reduce the risk of immunogenicity

doi:10.1128/genomea.00788-17 Li, Y., Wei, G., & Chen, J

Effects of S-acetylglutathione in cell and animal model of herpes simplex virus type 1 infection

The extended FAD molecule also shows a mobility gradient between the very rigid flavin (mean value of B) = 8.7 A2) and the more mobile adenine (mean value of B = 16.2 A2)