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Phytochelatin synthase in heavy metal detoxification and xenobiotic metabolism, Mendes, K.F., Sousa, R., Mielke, M.C

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Cleland, J

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DFO has demonstrated neuroprotective effects with the alleviation of behavioral deficits in a PD mouse model (Guo et al., 2016), although its clinical use for CNS disorders is limited by poor BBB permeability and oral bioavailability, as well as neurotoxicity at high doses (Freedman et al., 1988)

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