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Effects of Copper and Zinc Imbalances on Neurotransmitters The imbalances in copper and zinc can also have an impact on neurotransmitter levels

For instance, amifostine exhibits remarkable individual differences in efficacy and toxicity: it requires alkaline phosphatase (ALP) for conversion in vivo to exert its effects, and varying ALP levels among tumor patients affect the production of its active metabolites, thereby influencing therapeutic efficacy (192)

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