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Telomeres (the protective caps at the end of DNA strands) also become damaged, which is another factor that contributes to premature aging and all the health risks that come with it

doi: 10.1038/s41568-021-00435-0

Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model