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Corticosteroids are typically used for limited periods of time due to the risk of possible side effects

Int J Mol Med 31(1):265271 Del Campo-Rota IM, Delgado-Casillas OM, Ibarra A (2024) Cognitive impairment induced by gestational diabetes: implications of oxidative stress as an inducing mechanism

Although numerous preclinical studies have shown that iron chelators such as deferoxamine (DFO), deferiprone (DFP), and PBT2 effectively mitigate brain iron overload, reduce amyloid burden, and improve cognition in AD models, translation to the clinic has proven challenging