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PLCs are classically coupled to GPCRs, therefore we tested orphan GPCR Olfr39 overexpressing cells identified in the same screen [32] and observed the prototypical pattern of Ms4a15 OE in viability, Ca 2+ , and lipid regulation (Supplementary Fig

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We hypothesize that the selenium-iodine-induced oxidative eustress acts as a signal that shunts metabolic precursors away from the phenylpropanoid pathway (which produces eugenol) and toward the methylerythritol phosphate pathway, which leads to linalool synthesis

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