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Alogliptin affects several signaling mechanisms that enabled researchers to exploit its effects on pathologies related to other organ systems [9]

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These mechanisms collectively explain the increased CV risk despite apparently favorable lipid profiles in untreated patients [216]

J Psychopharmacol 24:15771601 Wu YH, Swaab DF (2007) Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimers disease