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Without rigorous, peer-reviewed clinical trials, the long-term behaviour of these substances within the body remains less clear than that of MHRA-approved medications

Although hydroxyurea and 5-fluorouracil, not known to cause CIPN, did not affect neurite morphology in this model, platinum agents, taxanes, and bortezomib reduced neurite outgrowth and processes, suggesting induced pluripotent stem cell-derived neurons might be useful for the screening of potential neuroprotective drug candidates

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Keep this ABCDE rule in mind when checking moles: A for asymmetry : If you were to cut the mole down the middle, would the left and the right sides look different