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The results showed that Tanzeum bound with slightly faster association and dissociation rates than GLP-1 WT, resulting in a 1.5-fold difference in binding affinity to the receptor (Tanzeum: 76.1 nM

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Dialysis membranes (molecular weight cut- off 14 kDa, flat width 43 mm), acetic acid ( 99.7%), and phosphate- buffered saline (PBS, pH 7.4) tablets were also obtained from Sigma- Aldrich (Darmstadt, Germany)

Representative sources include peer-reviewed publications indexed by PubMed and scientific literature describing Tesamorelin, Ipamorelin, GHRH analogs, ghrelin receptor signaling, pituitary physiology, and growth hormone research