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HIV latency and integration site placement in five cell-based models

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Reactions synthesizing ATP (glycolysis, oxidative phosphorylation), contributing to the cellular redox state (the pentose phosphate pathway, malic enzyme, GSH synthesis), producing precursors for proliferation (fatty acids, nucleotides, serine), and involved in 1C metabolism were determined by analysis of respiration rates, glucose and glutamine consumption, lactate and serine efflux, and 13 C labeling of the latter two metabolites from [1,2- 13 C] glucose or [5- 13 C] glutamine

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