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2020 Apr 15 [cited

While pS6 levels in cDCs did not initially appear to correlate linearly with age (Supplemental Figure 4A), stratifying the data by age groups revealed a nonlinear relationship: pS6 levels increased during childhood and peaked around 20 years of age, followed by a decline in older individuals (Supplemental Figure 4B)

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However, the data summarized in these tables indicate that the antioxidant effectiveness of bacteria-derived metabolites has been primarily tested through in vitro activity assays and in some in vivo animal studies