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In recent years, there has been an increasing amount of research on using natural plant compounds to inhibit ferroptosis and alleviate kidney damage

ROS is produced at low levels in a healthy body and is responsible for adjusting cell signaling and proliferation

A continuous administration of SFN for 6 weeks significantly increased hepatic expression of FGF21 and facilitated fatty acid metabolism through preserving FGF receptor 1 protein and preventing the phosphorylation of p38MAPK in HFD-induced NAFLD mice (Wu et al., 2022)