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A longer, alternative transcript of GPx4 also was localised to mitochondrial membranes ( Reference Pushpa-Rekha, Burdsall and Oleksa 23 ) and shown to maintain ATP production during oxidative stress which could have implications on cellular activity and function during disease ( Reference Liang, Remmen and Frohlich 24 )

Biochem J 371:589595 Srikanth CV, Vats P, Bourbouloux A, Delrot S, Bachhawat AK (2005) Multiple cis-regulatory elements and the yeast sulphur regulatory network are required for the regulation of the yeast glutathione transporter, Hgt1p