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Similarly, western blot analysis revealed that NRTP significantly increased p-AKT and p-FOXO3A in the M group, and WCV treatment reduced their levels close to those of the control in the VM group, whereas PD-1 antibody treatment did not have a rescue effect on the PM group (Fig

in general, there is no obvious predisposing cause (Thijs et al., 2019)

Consequently, interventions targeting the HPA axis are of considerable clinical and theoretical significance for treating depression, offering a scientific basis for optimizing antidepressant strategies and advancing personalized medicine

Barki-Harrington et al., 2003)