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The brains were excised, weighed to obtain the wet weight, and then subjected to oven drying at 95100 C for 72 h, after which they were reweighed to determine dry weight

Curcumin treatment in APPswe/PS1dE9 mice also showed the tendency to decrease the level of soluble A 40 while concurrently soluble A 42 level was increased, which could be attributable to the insufficient time (duration of experiment was a week) to achieve significant biochemical changes of A despite the observation of significant A clearance [40]

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