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Behesti H, Fore TR, Wu P, Horn Z, Leppert M, Hull C, et al

Abstract Therapy resistance is attributed to over 80% of cancer deaths per year, emphasizing the urgent need to overcome this challenge for improved patient outcomes

Gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate and GnRH antagonist cetrorelix acetate directly inhibit leiomyoma extracellular matrix production

Further studies should investigate the regulation of Ala synthesis and transport in CD, particularly concerning mucosal damage and recovery, and assess its potential as a non-invasive biomarker for disease activity and nutritional status