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This work was also supported by the projects MH CZ-DRO (UHHK, 00179906) and Excelence PrF UHK 2208/2023-2024

3.6 Pyrosequencing Pyrosequencing is a highly precise, real-time sequencing-by-synthesis technology used for high-resolution DNA methylation analysis, mutation detection, and genomic research

Theoretical advantages include reduced toxicity, enhanced cytotoxicity due to the ability to deliver higher concentrations of drugs that would be toxic if administered systemically, and the synergistic benefit of combined tumor kill from the antibody and the payload

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