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Towards a neuroprotective gene therapy for Parkinsons disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

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However, certain strains of mice, most notably black C57 and Swiss Webster, are sensitive to MPTP [86]

Microbial dysbiosis is associated with immune dysregulation through the alteration of key metabolites, including SCFAs, secondary bile acids, tryptophan, and indole derivatives, all of which are crucial for maintaining Treg function and mucosal immune tolerance [113]