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MSCs could reduce the production of inflammatory factors such as IL, TGF, TNF and interferon (IFN), inhibit the proliferation of T and B cells, reduce IgG secretion, inhibit the maturation of dendritic cell and regulate the activities of other immune cells such as natural killer cells and macrophages (214)

Sex of the animal models To the best of our knowledge, the occurrence of osteosarcoma is not related to the sex of the patient

The symptoms of Long COVID, ME/CFS, and dysautonomia are deeply interconnected and fluctuate based on a variety of internal and external stressors

The secondary outcome measures will also be analysed using generalized linear mixed models