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Blood (2009) 113:121324

(5) Reduces the levels of excitatory neurotransmitters and increases the transmission of inhibitory neurotransmitters by inhibiting carbonic anhydrase (CA), especially CA II and CA IV (White, 2005)

Biochemical measurements At the end of the reperfusion period, animals were euthanized with a high-dose intraperitoneal injection of ketamine and xylazine (200 mg/kg and 20 mg/kg, respectively), and ileal tissues were harvested and stored at 80 C for biochemical analysis