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In animal studies, the drug has been shown to increase the risk of thyroid cancer

10.3390/dna2040020 78 Lpez-OtnC.BlascoM

This is relevant because the potency of equol is higher than its precursor daidzein

After washing the membranes four times with TBST buffer, they were incubated at room temperature for 2 h with anti-His tag antibody (1:2000, Abbkine) in TBST buffer