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Oral administration significantly reduces lipogenic activity and increases lipolytic activity in adipose tissue, with concurrent increases in fat and glucose oxidation and elevated energy expenditure

Moreover, TDNPs have been verified to activate the Nrf2/HO-1 signaling pathway to promote the proliferation and migration of fibroblasts by improving their endogenous antioxidant capacity and reducing cell apoptosis [40]

The IEMs involving excitotoxicity are organized in the following topics according to the groups established by the ICIMD [4]

44 It also bound to the extreme C-terminal region of p73 (aa 427548) repressing its activity without apparently initiating its degradation