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Overactive T cells in SLE can contribute to impaired immunological regulation, increased production of inflammatory cytokines, and an increase in effector T-cell phenotypes

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Moreover, nanocarriers alter the pharmacokinetic properties of drugs by enhancing their effectiveness and diminishing their adverse effects [423]

Tumor necrosis factor- stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase