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The impressive data supporting the role of deacetylation by HDACs in epilepsy arises from the study that the interaction of HDAC3 with MADS-box domain of MEF2 results in MEF2 deacetylation in nucleus and the decrease of MEF2 transcription [74]

This may support the claim that TI heifers mount an abnormal immune response, as lymphoid tissue is critical to appropriate immune response [105]

Omega-3 fatty acids help maintain the skin's lipid barrier, which is crucial for retaining moisture and protecting against environmental stressors