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This suggests that hyperthermia selectively targets leukemic cells more effectively than normal hematopoietic cells, and serums protective role is not sufficient to alter this outcome

doi:10.21037/tau.2016.07.10 Tong SF, Ng CJ, Lee BC, et al

The most frequently reported side effects are nausea, vomiting, diarrhea, and constipation, driven by the combined effect both drugs have on slowing gastric emptying

Hypothalamic neuronal activation studies: Immunohistochemical mapping of c-Fos or pCREB expression in brainstem and hypothalamic nuclei following administration to rodent models to delineate central amylinergic circuits