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Description

Heck, S

In spite of the intrinsically challenging task of ionisation of glycated proteins and peptides owing to their charged status (Rabbani et al., 2016)

This particular configuration allows for the transmission of an extracellular signal of the antigen to the Treg cells, which subsequently results in the stimulation of Treg cell activation without the need for interaction with the antigen in the MHC-dependent manner

Mode of action Ferrostatin-1 functions by scavenging lipid peroxyl radicals and preventing oxidative membrane damage, thereby protecting cells from iron-dependent oxidative stress and subsequent ferroptotic cell death [1]