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Oxid Med Cell Longev 2014(1):541230 Yamamoto M, Kensler TW, Motohashi H (2018) The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis

Strengthens the cardiovascular system: More muscle mass = higher metabolism = less body fat

OTHER REGULATORS OF THE PENTOSE PHOSPHATE PATHWAY It has been shown that the activation of mammalian target of rapamycin complex 1 (mTORC1) increases the metabolic flux through both glycolysis and the oxidative arm of the pentose phosphate pathway (Dvel et al., 2010)

Its use depends on clinical indication, medical history, lab markers, and regulatory appropriateness