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Poly(ADP-ribosyl)ation by PARP-1: PAR-laying NAD+ into a nuclear signal

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Fortifies Immune System Plays a critical role in the proper function of white blood cells, including T cell lymphocytes and the multiplication of lymphocytes (the cells that mediate specific immunity) Adequate function of white blood cells is essential in mounting an effective immune response Clinical Highlights In a 4-week human study conducted at Penn State University College of Medicine: 28% increase in red blood cell glutathione levels 400% increase in natural killer cell function 25% reduction in oxidative stress marker (lipid peroxidation) *Effects were observed as early as one week