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Taken together, hyperhomocysteinemia triggers the development and progression of PD by different mechanisms, including oxidative stress, mitochondrial dysfunction, apoptosis, and endothelial dysfunction [Fig

While mitophagy plays a crucial role in cellular health, it can also reduce the overall number of mitochondria, potentially decreasing ATP production

Bioinformatics studies have identified Yes-associated protein 1 (YAP1) as a potential key regulator of ferroptosis in VSMCs of unstable plaques

Severe condition/postoperative period: 750 mcg-1 mg daily (up to 4 weeks intensive mode), total therapy duration 2-6 weeks, break 2 weeks