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Phase II study of sorafenib in combination with cisplatin and 5-fluorouracil to treat recurrent or metastatic nasopharyngeal carcinoma

doi: 10.2337/dc10-1006 38 TanKSLeeKOLowKCGamageAMLiuYTanGYet al

Notably, in this loop, pyroptosis is primarily responsible for the rapid amplification of acute inflammation, whereas ferroptosis drives disease progression toward an irreversible direction through sustained depletion of structural cells