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Dimensionality reduction in microbiome data analysis involves two primary approaches: feature extraction and feature selection

TNF secreted from adipose tissue can induce hepatocyte apoptosis and exacerbate inflammation through activation of the NF-B and JNK pathways, among other pathways [217, 218]

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Nat Rev Immunol 16 : 2234 A comprehensive review of most updated concepts in immune mediation of depressive and mood disorders and ties it to our evolutionary origins