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Semax also modulates neuroinflammation through multiple pathways, reducing the chronic inflammatory signaling that drives ongoing nerve damage in many neuropathy subtypes

These changes, in addition to the release of numerous cytokines, such as IL-1, IL-6, TNF and TGF-1, and the release of extracellular matrix metalloproteinases that damage the basement membrane.61 Radiation-Induced Morphea A recent review of the literature, published in 2014, found 66 cases of radiation-induced morphea.62 Similarly to sclerodermiform-like panniculitis, this complication of radiotherapy has been reported most often in patients with breast cancer, although it has also been described in the context of other tumors.62 The typical presentation is an erythematous patch that gradually hardens (Fig

T., Berson, E

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