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Future research should explore the bidirectional crosstalk between sex hormones and mitochondrial signaling, paving the way for more precise and safer therapeutic strategies tailored to individual pathophysiological profiles

10.1016/s0305-4179(01)00055-9 78 MiyamotoS.TakaokaK.OkadaT.YoshikawaH.HashimotoJ.SuzukiS.et al (1992)

In an ongoing Phase 2a study assessing IDR as lead-in (24 weeks) followed by 12 or 24 weeks of IFN additional IDR doses in HBeAg-negative CHB subjects virally suppressed on nucleos(t)ide analog (NA) therapy (AB-729-201, IM-PROVE I), soluble immune biomarkers were profiled and association with HBsAg response assessed