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SKU: 45741885750
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Availability: InStock
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Description

Biological oxidants promote the binding of SOD1 with the effector kinases Mec1 (Mitosis entry checkpoint 1)/ataxia-telangiectasia mutated (ATM) (ATM kinase is known as an oxidation sensor directly activated by hydrogen peroxide) and Cds1/Dun1, as well as the phosphorylation of Dun1 at S 59 and S 98 sites on SOD1, promoting the nuclear localization of SOD1 [26,27]