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McLaughlin and Blot (1997) suggested that the first three cases diagnosed in 1990 and 1991 might represent the original cluster

Abbreviations ROS: reactive oxygen species GCLC: glutamate-cysteine ligase GPXs: glutathione peroxidases GSR: glutathione reductase GSTs: glutathione S-transferases IACUC: The Institutional Animal Care and Use Committee H&E: hematoxylin and eosin SEM: scanning electron microscope TEM: transmission electron microscope AFM: atomic force microscopy PDTG: partially decellularized tracheal grafts PCR: polymerase chain reaction References Martinod, E