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The pertinent findings of this study are: 1) enhanced hepatic de novo serine synthesis is required for SAAR to improve glucose tolerance, 2) concurrent with transcriptional activation, a serine synthesis-GSH-lysine lactoylation feedback loop may underlie the increased hepatic serine synthesis in response to SAAR, and 3) hepatic serine synthesis is not necessary for the SAAR-mediated decline in adiposity and liver triglycerides

Do not scrub hard or over-treat, as that will cause irritation or aggravate pigmentation

Ryu J, Ku BM, Lee YK, Jeong JY, Kang S, Choi J, et al

doi: 10.3390/pr9101840 32 DobroslaviE.ZoriZ.Dragovi-UzelacV.Elez GarofuliI