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Nat Rev Nephrol (2021) 17(1):4664

Poly(3-hydroxybutyrate) granule-associated proteins: impacts on poly(3-hydroxybutyrate) synthesis and degradation

Aggressive medical management according to established protocols for ALF (including treatment of hyperammonemia and detection and management of cerebral edema), with early consideration of apheresis or renal replacement therapy to rapidly remove circulating copper, may stabilize the patient with WD awaiting transplantation