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[DOI] [PubMed] [Google Scholar] 67.Dinicola S., Proietti S., Cucina A., Bizzarri M., Fuso A.J.A

In MMAemia, toxic metabolites (e.g., MMA, 2-MCA, PA, Hcy, ammonia, lactate) serve as primary triggers of cerebral injury

An orthomolecular approach to the prevention and treatment of psychiatric disorders

In a zebrafish model, compared with C3-carnitine, C18-carnitine and C18:1-carnitine can induce the inhibition of OXPHOS, interfere with the energy supply of cardiomyocytes, and lead to a significant impairment of cardiac systolic function, which manifests as a decreased heart rate and reduced shortening of the atrial and ventricular fractions [21]