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Why reduced glutathione matters: Glutathione exists in two forms: reduced (GSH, the active antioxidant form) and oxidised (GSSG)

Science 372 (6539), 372

Gold nanostars loaded with triamcinolones, when coupled with MSC to promote the repolarization of macrophages, can inhibit the Th17 differentiation and induce the regeneration of cartilage (105)

However, the effectiveness of these enzymes is likely limited by the characteristic GSH deficiency in CF, both in pulmonary epithelial lining fluid and systemically in plasma (Hewson et al., 2020)