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In Japanese patients with hyperuricemia who were studied in detail, heritable ABCG2 dysfunction was observed in up to half of the study population investigated, and its population-attributable contribution to hyperuricemia was as high as 30%, much higher than the contribution of non-genetic factors such as overweight/obesity, heavy alcohol consumption and aging

Plasma supernatant was collected, divided into aliquots, and frozen at 80 C until further NfL determination, metabolic profiling, or targeted metabolomics

[DOI] [PubMed] [Google Scholar] Reyes-Gordillo K, Segovia J, Shibayama M, Vergara P, Moreno MM, Muriel P

The Serratia marcescens bioH gene encodes an esterase