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The supernatant fluid was removed and the protein pellets were suspended in 1 ml of 1:1 (vol/vol) ethanol/ethyl acetate followed by centrifugation at 10,000 g for 10 min at 4C

Furthermore, several inhibitors targeting inflammatory signaling pathways, such as Baricitinib, Sirukumab, and Emapticap pegol, have demonstrated efficacy in clinical trials for improving eGFR, UACR, and retarding the progression of kidney disease (199201)

At the same time, adaptive immune cells (T cells and B cells) are also involved in the pathogenesis of CP

In addition, we observed spheroid-shaped worms (rather than vermiform), which were markedly granulated, as described by other investigators [44, 45]