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Cardiovascular exercise can be incorporated but is not necessarily superior to resistance training for fat loss purposes

It is also essential in turning carbohydrates into glucose and keeps the nervous system running smoothly

Continuous long-term use is reserved for specific clinical situations under careful monitoring

The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions