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46,47,48 Through an antioxidant cascade, melatonin metabolites such as N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK) further neutralize free radicals, protecting mitochondrial integrity, proteins, and DNA from oxidative destruction

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For instance, the in vivo localization accuracy of chemical propulsion systems, fuel safety, immunogenicity and off-target effects of nucleic acid platforms, and the immune responses and long-term host effects associated with membrane camouflage systems must all undergo rigorous toxicological studies and pharmacokinetic assessments ( Table 2 provides a systematic comparison of the actuation mechanisms, advantages, and target applications characterizing various biomimetic nanorobotic strategies