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Inflammation-stimulated mesenchymal stromal cell-derived extracellular vesicles attenuate inflammation

Mechanism Aberrant -synuclein aggregation A hallmark pathological feature of PD is the presence of Lewy bodies within neurons, largely consisting of misfolded and aggregated -synuclein 42

No.: 51

Interestingly, the STAT3 transcription factor is the major inducer of the expression of this immunosuppressive armament, either directly or indirectly [9, 89, 93, 94]