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This fluorescence-based technique requires low protein concentrations and offers high sensitivity, well-suited for studying concentration-dependent aggregation-prone IDPs like Syn

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Meanwhile, studies have reported that 2,2-Bipyridine exerts ferroptosis inhibition by chelating intra-mitochondrial iron ( 1,10-Phenanthroline resembles and downregulates mitochondrial ROS accumulation and inhibits ferroptosis induced by zero-valent iron nanoparticles in vitro with 2,2-Bipyridine (Huang et al., 2019